The medicine cimetidine is a commonly used medicine to take care of gastrointestinal conditions. The affect of this medicine is to stop the creation of stomach acid. One of them disorders is called gastroesophageal reflux disease and it is the retrograde movement of gastric contents from the stomach back up in the oesophagus that inflames the lining in the oesophagus resulting in acid reflux which is more commonly referred to as heartburn, particularly right after bedtime. It can also leave a sour or bitter taste in the mouth. This will affect as much as 10-20% of the population. There are lots of risk factors which raise the probability of this occurring, and so they all should be sorted out in the long run to deal with the problem. In the short term, it would seem sensible to help reduce what amount of the stomach acid is produced to lessen the symptoms. That is where cimetidine will come in. This drug hinders receptors in the tissue of the gastric lining which in turn obstructs gastric acid secretion. Which means that there is much less stomach acid to irritate the oesophagus and result in the symptoms. Cimetidine is familiar in the name brand, Tagamet from pharmaceutical drug organization Glaxosmithkline Inc, however there are many other less well known brands on the market. It was first sold in 1976 and very quickly has become the first of the so-called ‘blockbuster’ prescription drugs and creating a considerable amount of money for the company. It was actually originally a doctor prescribed only medicine however it currently is accessible as an over-the-counter medicine without a prescription. The medication is not utilized as very much these days as it was previously because other drugs have been produced which commonly give you a improved outcome for the gastroesophageal reflux disease which include omeprazole that works as a proton pump inhibitor.
In the 1990’s cimetidine began to be suggested for some skin-related problems for example warts or verruca which are the result of a viral infection. The advised dosage coming from the ones that suggest its use is to take forty mg/kg/day, but you need to seek advice from a health care specialist initially. The supposed mechanism with this could be that the medicine stimulates the immunity process and a couple of scientific studies have shown there were different amounts of biomarkers of immune system stimulation in the skin of those people who had warts which ended up getting better. There were lots of testimonials in which warts or verruca going away while using this medication. There initially were a number of early studies that didn’t have control group that showed it appeared quite effective at managing warts. The thing is that warts have a tendency to go away by themselves sooner or later (which can be quite a long time) and are often quite responsive to a placebo. The question really should be asked does cimetidine for warts help or is it really a high priced placebo. Lately studies have been done with control groups that were blinded and provided a placebo believing it had been the medicine and unfortunately demonstrated that taking Tagamet for verruca is no as good as taking a placebo. In case you have warts or verrucae, then get advice from your healthcare professional as to your better therapy choice.
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